Chapter 1 Introduction 1．1 Research Motivation 1．2 Objectives Chapter 2 Literature Review 2．1 Introduction 2．2 Hydrodynamic Characterizations 2．3 CFD Modeling Approaches 2．4 Closure Model 2．5 Summary Chapter 3 Numerical Study of Special Ball Packed Bed Reactor 3．1 Experiments Data Collection 3．2 Development of the Numerical Model 3．3 Results and Discussion 3．4 Conclusions Chapter 4 Numerical Simulations of a Structured Packed Bed 4．1 CFD Model Development 4．2 Results and Discussion 4．3 Conclusions Chapter 5 Development of Macro-scale Model 5．1 Macro-scale Model Description 5．2 Modified Closure Model 5．3 Results of a New Closure Model 5．4 Conclusions Chapter 6 Conclusions Nomenclature References
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